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:: year 12, Issue 48 (8-2020) ::
3 2020, 12(48): 55-61 Back to browse issues page
Study of serum levels of antibodies against Helicobacter pylori in patients of Islamshahr Health Center in Tehran
Mojgan Sadeghi Ms 1, Amir Aliramezani Dr2, Sepideh Hasanpour Ms3
1- Tehran university medical sience, Islamshahr health center
2- Tehran university medical sience, Hospital Emam Khomeini
3- Islamshahr health center
Abstract:   (305 Views)
Background and Goals: Helicobacter pylori is a gram-negative micro-aerophilic bacillus, with a global prevalence. The bacterium causes a wide range of gastrointestinal diseases, including chronic gastritis, peptic ulcer, gastric cancer and MALT. Due to the importance of this bacterium in causing gastrointestinal disorders, this study was conducted to evaluate the serum levels of antibodies against Helicobacter pylori in clients of Islamshahr Health Center by ELISA.
Materials and Method:In this cross-sectional study, the serum of 650 patients referred to Islamshahr Health Center who had clinical symptoms was collected. The IgG, IgA and IgM antibodies to Helicobacter pylori were then measured using the ELISA method.
Findings: From all the samples performed (650 samples), the results were as follows: 47.08% (306) IgG, 14.62% (95) IgA, 4.62% (30) IgM. The highest IgG antibody frequency was observed in the age group of 46-60 years (65%). No significant association (P = 0.6) was observed between the mean titers of IgA, IgM and IgG antibodies with age.
Conclusion:Due to the high percentage of positive titers of IgG and IgA antibodies against Helicobacter pylori, it is necessary to use codified educational and health programs to reduce the prevalence of this bacterium.
Keywords: Helicobacter pylori- gastrointestinal- IgG- IgA- IgM
Full-Text [PDF 639 kb]   (185 Downloads)    
Type of Study: Review | Subject: قارچ شناسی
Received: 2020/09/16 | Accepted: 2020/09/16 | Published: 2020/09/16
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Sadeghi M, Aliramezani A, Hasanpour S. Study of serum levels of antibodies against Helicobacter pylori in patients of Islamshahr Health Center in Tehran. 3. 2020; 12 (48) :55-61
URL: http://labdiagnosis.ir/article-1-408-en.html

year 12, Issue 48 (8-2020) Back to browse issues page
Laboratory & Diagnosis
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