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The role of vitamin D3 in the prevention, protection and reduction of long-term clinical manifestations of Covid-19
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Daryoush Farhud   1, Rana Hajilo2 |
1- Academy of Medical Sciences Islamic Republic of Tehran, Iran
2- Islamic Azad University Tehran-East, Tehran, Iran |
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Abstract: (50 Views) |
Background: Since January 2020, the 2019 coronavirus pandemic (COVID-19) has put the majority of global health economic systems under strain. Acute respiratory syndrome coronavirus (SARS-CoV-2) is the cause of COVID-19, which affects several bodily systems and may produce severe acute respiratory and cardiac symptoms that can lead to patient death. The study's findings indicate that vitamin D3 is a potentially useful chemical for preventing, protecting against, and reducing covid-19 disease.
Methodology: Given the massive damage produced by COVID-19 to the immune system, there is a lot of interest in vitamin D's ability to alleviate or avoid detrimental immunological responses. Data sources and study selection PubMed, Embase, Clements, Bmj, and other databases were searched from March 26, 2011 to June 9, 2023, with eligibility criteria used to select studies using the search terms (cholecalciferol or ergocalciferol or vitamin D2 or vitamin D3 or vitamin D or 25OHD) and (SARS-CoV-2 or coronavirus or COVID or respiratory infection).
As a result, the goal of this review is to combine the information around vitamin D in connection to COVID-19 in order to evaluate the current consensus on vitamin D supplementation as a strategy to treat and/or prevent the start or progression of COVID-19.
In this article, we provide an overview of the state of knowledge in this topic, including major papers and systematic reviews published until now.
Findings of epidemiological studies: The findings of this research revealed that persons with vitamin D3 insufficiency had worse health outcomes and died from COVID-19. Higher vitamin D3 dosages may increase health and survival in the elderly and persons suffering from underlying disorders.
Conclusion: The biological impacts of vitamin D3 can protect and repair many body systems of people influenced by SARS-CoV-2. Vitamin D3 supplementation can potentially support the reduction of acute and long-term covid-19 disease. |
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| Keywords: vitamin D, public health benefits, SARS-CoV-2, COVID-19, long-term |
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Full-Text [PDF 466 kb]
(33 Downloads)
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Type of Study: Review |
Subject:
ژنتیک
Received: 2024/12/28 | Accepted: 2024/12/29 | Published: 2024/12/29
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