In this section, the small conidia producing fungi will be discussed. These includes Cladosporium spp, which may be important human pathogens or common laboratory contaminants and Cladophialophora spp. Which are the most common causes of chromoblastomycosis and cerebral phaeohyphomycosis. Then, we will discuss about the Chaetomium spp. uncommonly responsible for human mycoses, Nattrassia magniferae, a common agent of dermatomycoses and onychomycosis in patients living or immigrating from tropical areas, Phoma, which rarely isolated from humans, and Coniothyrium (which caused infections in immunocompromised individuals) which have complex reproductive structures. Dematiaceous agents of mycetoma are the last organisms which will be explained here, these includes: Madurella mycetomatis and M. grisea, also Leptosphaeria and Pyrenochaeta species.