[Home ] [Archive]    
:: year 9, Issue 37 (12-2017) ::
3 2017, 9(37): 7-13 Back to browse issues page
CRISPR/Cas9 technology and its application in treatment of genetic diseases
Sadegh Valian Borujeni Dr 1, Farzaneh Mohammadi Farasani Dr1
1- Department of biology, Faculty of science, University of Isfahan, Isfahan, IR Iran
Abstract:   (1725 Views)
The development of recombinant DNA technology in the 1970s marked the beginning of a new era for biology. For the first time, molecular biologists gained the ability to manipulate DNA molecules, making it possible to develop novel medicine. Nowadays, the introduction of targeted genomic sequence changes into living cells and organisms has become a powerful tool for biological research and provided a potential avenue for therapy of genetic diseases. Of these new technologies, the most exciting is CRISPR/Cas9, a gene editing system adopted from bacterial immune system that is efficient, rapid, and easy-to-use. CRISPR/Cas9 technology allows targeted knock-in and knock-out and/or changes of any gene within the genome. In this study, this technology and its applications in treatment of genetic disease was discussed.
Keywords: Gene editing, CRISPR/Cas9, treatment of genetic diseases
Full-Text [PDF 464 kb]   (2641 Downloads)    
Type of Study: Review | Subject: ژنتیک
Received: 2017/12/20 | Accepted: 2017/12/20 | Published: 2017/12/20
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Valian Borujeni S, Mohammadi Farasani F. CRISPR/Cas9 technology and its application in treatment of genetic diseases. 3. 2017; 9 (37) :7-13
URL: http://labdiagnosis.ir/article-1-244-en.html

year 9, Issue 37 (12-2017) Back to browse issues page
Laboratory & Diagnosis
Persian site map - English site map - Created in 0.06 seconds with 31 queries by YEKTAWEB 3925