Obesity and related metabolic diseases, such as type 2 diabetes,hypertension and hyperlipidemia, and, consequently, increased risk of cardiovascular disease are common in medical and social issues in developed and developing countries. Therefore, understanding the underlying molecular basis of obesity and related metabolic diseases is important in order to develop preventive and effective therapies against such conditions.
Angpt is a member of the family of vascular growth factors that is involved in the process of angiogenesis in the embryonic and postnatal period. Angiopoietin signaling is directly related to angiogenesis, the process by which the arteries and vessels of the vein Previous blood disorders are caused
Recently, a family of proteins that have a similar structure with angiogenic regulatory factors, the angiopoietins, have been identified and are referred to as angpt-type proteins. Several studies have shown that most of these proteins have a functional potential for arterial regulation, and subgroups of them have a role in regulating glucose, lipid, and energy metabolism.
The regulation of the metabolism of mammalian energy is a complex process involving multiple hormones, transcription factors, and signal transmission cascades. Many of the settings are based on the secretion of information that transfers information from one organ to another.