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From Microbes to Minds: Gut Bacteria on Infant Cognitive Growth.
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Monireh Rahimkhani1   , Maryam Hosseini2 |
1- Faculty Member of Lab Medical Sciences Department, Faculty of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
2- Faculty of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran |
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Abstract: (28 Views) |
The interplay between the gut microbiota and brain development during infancy is a burgeoning area of research that highlights the critical role of microbial communities in shaping neurodevelopmental outcomes. This review synthesizes current findings on how maternal microbiota and early microbial exposure influence the infant gut microbiome, which in turn affects cognitive and behavioral development. Evidence suggests that disruptions in the gut microbiota during critical developmental windows can lead to adverse neurodevelopmental consequences, including increased risks for conditions such as autism spectrum disorders and attention-deficit hyperactivity disorder. Furthermore, the review discusses mechanisms underlying the microbiome-gut-brain axis, emphasizing the importance of early-life nutrition and environmental factors in establishing a healthy microbiome that supports optimal brain development. This comprehensive overview aims to inform future research directions and potential interventions targeting the gut microbiota to promote better neurodevelopmental outcomes in children. |
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| Keywords: Gut Microbiota, Brain Development, Maternal Influence, Microbiome, Gut, Brain Axis, Cognitive Function, Immune Development |
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Full-Text [PDF 513 kb]
(15 Downloads)
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Type of Study: Review |
Subject:
میکروب شناسی و باکتری شناسی
Received: 2025/09/22 | Accepted: 2025/09/25 | Published: 2025/09/25
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