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Microangiopathic anemia
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Nahid Nasiri1   , Habibollah Golafshan1 |
| 1- Department of Medical Laboratory Sciences, School of Paramedical Sciences, Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran |
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Abstract: (162 Views) |
Microangiopathic hemolytic anemias fall under the category of life-threatening anemias. Early diagnosis of these anemias, which present with fragmented red blood cells such as helmet shapes, triangular forms, microspherocytes, and keratocytes on peripheral blood smears, provides a critical opportunity for the timely treatment of diseases such as disseminated intravascular coagulation (DIC), HELLP syndrome, thrombotic thrombocytopenic purpura (TTP), and hemolytic uremic syndrome (HUS). Schistocytes are so significant that a finding of more than 2 percent is classified as a high grade.
It is important to note that reporting schistocytes in a normochromic and normocytic morphology is crucial, as it indicates damage to the capillaries due to fibrin deposition or white platelet clots and von Willebrand factor.
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| Keywords: Microangiopathic, Fragmented Cells, Fibrin Deposition, White Platelet Clot |
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Full-Text [PDF 1788 kb]
(94 Downloads)
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Type of Study: Review |
Subject:
خون شناسی (هماتولوژی)
Received: 2026/04/13 | Accepted: 2026/04/13 | Published: 2026/04/13
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