Chromoblastomycosis is a chronic infection of the skin and subcutaneous tissues caused by one of several dematiaceous fungi,which is distinguished by the unique finding of muriform”sclerotic bodies”on microscopic examination of material from lesions. It has a worldwide distribution but has been reported most frequently from tropical or subtropical locations.Particularly high incidence rates have been reported from Brazil,Madagascar, and Costa Rica, the causative organisms have been isolated from soil and decaying vegetation in these and other high prevalence areas. A recognized penetrating injury at the involved site has occasionally preceded the development of the chromoblastomycosis lesion. Person-to-person spread of chromoblastomycosis has not been documented. Lesions developemost commonly on the distal lower extremities, a location compatible with exposure of damaged skin to soil. The primary skin lesion is a small papule that gradually enlarges over weeks to months to form a superficial nosule with an irregular, friable surface. Lesions continue to evolve, often over many years, and at a given time may have morphologic features of one or more of five types of chromoblastomycosis lesions described by Carrion. Although the appearance and location of the skin lesions and the typically chronic history may be most suggestive of chromoblastomycosis, the differential diagnosiscan include tuberculosis, mycetoma, leprosy, blastomycosis, and cutaneous leishmaniasis.Examination of material from the lesionsis therefore necessary to make a definitive diagnosis in most cases, and culture should be performed to determine the causative agent.