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Biomarkers of Diabetic Foot Ulcer
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Zahra Rezvani   1, Fatemeh Khani1 , Mohammad Ali Takhshid2 |
1- Faculty of Chemistry, Kashan University
2- Faculty of Paramedical Sciences, Shiraz University of Medical Sciences |
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Abstract: (78 Views) |
Diabetic foot ulcer (DFU) is a major chronic complication of diabetes mellitus and a leading cause of disability and mortality among diabetic patients. Early diagnosis of diabetic foot ulcers can reduce hospitalization time and prevent disability and mortality of diabetic patients. Inflammatory biomarkers such as procalcitonin, pentraxin-3, C-reactive protein (CRP), interleukins, and tumor necrosis factor-α (TNF-α) have been suggested for early detection of the condition and distinguishing between infectious and non-infectious diabetic foot ulcers. With advances in biotechnology, the efficacy of newer biomarkers like microRNAs in diagnosing and targeting the treatment of diabetic foot ulcers has also gained attention. This review study will introduce these biomarkers and discuss the advantages and limitations of each method.
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| Keywords: Diabetic Foot Ulcer, Procalcitonin, C-Reactive Protein, Ischemia Modified Albumin |
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Full-Text [PDF 746 kb]
(41 Downloads)
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Type of Study: Review |
Subject:
بیوشیمی
Received: 2024/09/23 | Accepted: 2024/09/24 | Published: 2024/09/24
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