[Home ] [Archive]    
Main Menu
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Contact us::
Site Facilities::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
:: year 15, Issue 62 (2-2024) ::
3 2024, 15(62): 43-48 Back to browse issues page
- Fungal Infections in the Immunocompromised Patient-Section 1
Mohammad Ghahri
Abstract:   (654 Views)
Solid organ transplantation has made remarkable progress over the past three decades, evolving from a fascinating experiment in human immunobiology into the most effective means of rehabilitating patients with end-stage organ dysfunction of a variety of types. Today, at the best transplant centers, more than 90% long-term patient and allograft survival are being achieved following kidney, heart, and liver transplantation, with about 75% of lung-transplant recipients achieving these positive results. Because of these successes, the transplant community has been encouraged to ‘‘extend the envelope,’’ by bringing new forms of transplantation to the care of affected individuals. 
Invasive fungal infections remain a serious challenge to clinicians caring for immunocompromised patients. The proportion of vulnerable patients is increasing, paralleling the increased use of immunosuppressive therapies and the more effective supportive care in high-risk populations. Fungi responsible for these infections can be separated in two groups: the pathogenic and the opportunistic. The true pathogenic fungi cause self-limited disease in normal hosts but may cause devastating infections in compromised patients. Examples of such pathogens include Cryptococcus neoformans and the endemic fungi Histoplasma capsulatum, Coccidioides immitis, Paracoccidioides brasiliensis, and Blastomyces dermatitidis. These infections may remain in a latent state only to recru- desce when the patient is immunosuppressed. Opportunistic fungi rarely cause serious disease in normal hosts but are responsible for life-threatening infection in the setting of weakened host defenses. These fungi include Candida spp. and Aspergillus spp. and less commonly Zygomycete spp., Trichosporon spp., Fusarium spp., and Pseudoallescheria boydii among others.

Keywords: immunocompromised host, opportunistic mycoses, opportunistic infections, Aspergillosis
Full-Text [PDF 882 kb]   (423 Downloads)    
Type of Study: Review | Subject: قارچ شناسی
Received: 2024/03/11 | Accepted: 2024/03/11 | Published: 2024/03/11
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghahri M. - Fungal Infections in the Immunocompromised Patient-Section 1. 3 2024; 15 (62) :43-48
URL: http://labdiagnosis.ir/article-1-565-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
year 15, Issue 62 (2-2024) Back to browse issues page
Laboratory and Diagnosis
Persian site map - English site map - Created in 0.04 seconds with 36 queries by YEKTAWEB 4657